The University of North Carolina Herbarium
(NCU) has catalogued only about half a dozen specimens collected by Don E. Eyles. They were collected in 1940 and 1941, and about
half were collected with Mary S. Eyles. Eyles was by profession a parasitologist,
but was a serious student of ornithology and botany.
Don Eyles was born 4
September 1915 to Francis L. and Mory A. Eyles. The 1920 US Federal Census lists the Eyles family as living in Atlanta, Georgia, and consisting
of parents Francis L. (age 37), Mory A. (35),
Francis L. (11), Don E. (4), and Ruth (1 month).
“In 1937 [Fort Pulaski National Monument in
Chatham County, Georgia], employed student technician Don Eyles
to study plant life and the shorebirds on Cockspur Island and surrounding
areas. His research recorded black
skimmers, least turns, oyster catchers, marsh hens, and a large heron colony. This study helped the [National Park
Service] add the marshland of McQueen’s Island to the Monument to protect its
Don Eyles suffered a
fatal heart attack while in Penang, Malaya on 4 October, 1963, and was buried
in Arlington National Cemetery (Section 35, Site 2147) in Virginia. He was survived by his spouse, Mary, sons
Don E. Jr. and John, and daughter Mary Anne.3
J. (1963) Dr. Don E. Eyles. Nature
200 (4908): 733. 1
Dr. Don E. Eyles died
on October 4, 1963, of coronary thrombosis on board ship in Penang, Malaysia,
a few hours before he and his family were due to return to the United States.
This sudden death of an outstanding scientist and excellent colleague was
particularly tragic, as Dr. Eyles was about to
retire after twenty-four years' work for the U.S. Public Health Service to
join the Lahore (Pakistan) Unit of the Institute of International Medicine of
the University of Maryland School of Medicine.
Dr. Eyles was born in 1915 in Atlanta, Georgia, and
obtained his M.S. (Biology) at Emory University and his Sc.D. at the Johns
Hopkins University in Baltimore.
During the early period of his academic life he
was interested in ornithology and medical entomology, but later much of his
work was connected with investigations on malaria imported into the United
States by returning Service-men, and with curative action of drugs against
relapsing malaria infections. The difference between the effect of pyrimethamine and primaquine on
the tissue forms of malaria parasites became clear as a result of this work.
The curative action of pyrimethamine and sulphadiazine, and the synergistic effect of these drugs
in toxoplasmosis, were reported by Eyles et al. in
1952, and these findings were promptly confirmed in acute and chronic forms
of the disease. Much knowledge of the epidemiology of toxoplasmosis was due
to the work of Eyles on the relationship between
the infection in domestic animals and its transmission to man.
In 1960 Dr. Eyles,
taking a clue from his accidental laboratory infection,
showed that Plasmodium cynomolgi bastianellii of monkeys can be transmitted to
man through a mosquito. This stared much now and still expanding research on
the possibility of simian malaria as an anthropozoonosis.
In 1961 Dr. Eyles was
given the task of establishing a research unit of the U.S. Public Health
Service in Malaya and he went to the Far East companied by his wife and three
children. The research unit was set up at the Institute for Medical Research
in Kuala Lumpur and within less than three years Eyles
and his Malaysian, American, British and Australian colleagues produced a
remarkable series of investigations which have greatly extended our knowledge
of simian malaria. Five new species of malaria parasites of Malaysian monkeys
and of a moose-deer were discovered and their relationship to a number of anopheline vectors was established.
A new area for further research of considerable
fundamental and practical importance was thus opened in a field that until
recently seeded to be uninspiring and well-trodden. The impetus given in this
was to the investigation of simian malaria was characteristic of Eyles’s vision, determination, leadership and phenomenal
energy. During the past year Eyles was greatly
interested in the problem of resistance of human plasmodia to synthetic drugs
and particularly 4-aminoquinolines. He left a number of papers which are now
Some of us who saw Eyles
in September at the International Congresses of Tropical Medicine in Rio de
Janeiro and who heard his summary of the work carried out in Malaya could not
help saying that he seemed to be in a hurry to complete one job and to start
another. He was in a hurry, indeed for this “appointment in Penang”.
Eyles’s work resulted in more than a hundred publications. He
has demonstrated his qualities as an administrator of a research laboratory
and his brilliance and versatility as an investigator of general and specific
problems in parasitology. One of Eyles’s most
important assets was his ability to work with a team; he has undoubtedly
stimulated in others as much research as he has been personally responsible
for. His proficiency in experimental work in parasitology was equaled by his
general knowledge of ornithology, botany and entomology. He was an intensely
live individual – an inveterate collector of almost anything, biological or
otherwise – universally liked and admired by those who have had the good
fortune to know him during his short, happy and fruitful life.
PUBLICATIONS (incomplete list)
Eyles, Don E.; Dunn, F. L.; Warren, McWilson;
Guinn, Elizabeth SO (1963) Plasmodium coatneyi from the Philippines. The
Journal of Parasitology 49(6): 1038.
Eyles, Don E. (1963) The Species of Simian Malaria: Taxonomy,
Morphology, Life Cycle, and Geographical Distribution of the Monkey Species.
The Journal of Parasitology 49(6): 866-887.
Eyles, Don E.; Warren, McWilson
(1963) Hepatocystis from Macaca
irus in Java. The Journal of Parasitology
Eyles, Don E.; Warren, McWilson
(1962) Plasmodium inui in Sulawesi. The
Journal of Parasitology 48(5): 739.
Wharton, R. H.; Eyles, Don E.; Warren, McWilson; Moorhouse, D. E.
(1962) Anopheles leucosphyrus Identified
as a Vector of Monkey Malaria in Malaya. Science 137 (2532): 758.
Sandosham, A. A.; Wharton, R. H.; Warren, M.; Eyles, D. E. (1962) Microfilariae in the Rhesus Monkey (Macaca mulatta)
from East Pakistan. The Journal of Parasitology 48 (3): 489.
Eyles, Don E.; Coatney,
G. Robert; Getz, Morton E. (1960) Vivax-Type Malaria Parasite of
Macaques Transmissible to Man. Science 131 (3416): 1812-1813.
Eyles, Don E. (1960) Anopheles freeborni
and A. quadrimaculatus as Experimental
Vectors of Plasmodium cynomolgi
and P. inui. The Journal of Parasitology
Wharton, R. H.; Eyles,
Don E. (1961) Anopheles hackeri, a Vector
of Plasmodium knowlesi in Malaya. Science
Jones, Frances E.; Melton, Marjorie L.; Lunde,
Milford N.; Eyles, Don E.; Jacobs, Leon SO (1959)
Experimental Toxoplasmosis in Chickens. The Journal of Parasitology 45(1):
Eyles, Don E.; Coleman, Nell; Cavanaugh, D. J. (1956)
Preservation of Toxoplasma gondii by Freezing . The Journal of Parasitology 42(4): 408-413.
Eyles, Don E.; Coleman, Nell (1956) Relationship of Size of
inoculum to Time to Death in Mice Infected with Toxoplasma gondii. The Journal of Parasitology 42(3): 272-276.
Young, Martin D.; Eyles,
Don E.; Burgess, Robert W.; Jeffery, Geoffrey M. (1955) Experimental Testing
of the Immunity of Negroes to Plasmodium vivax. The Journal of
Parasitology 41(3): 315-318.
Eyles, Don E.; Gibson, Colvin L.; Jones, Frances E.; Cuningham, M. E. G.(1954) Prevalence of Dirofilaria immitis
in Memphis, Tennessee. The Journal of Parasitology 40(2): 216-221.
Eyles, Don E.; Jones, Frances E.; Jumper, John R.; Drinnon, Virginia P. (1954) Amebic infections in dogs.
The Journal of Parasitology 40(2): 163-166.
Eyles, Don E. (1954) Serologic Response of White Rats to
Toxoplasma Infection. The Journal of Parasitology 40(1): 77-83.
Eyles, Don E. (1952) Toxoplasma in the Norway Rat. The Journal
of Parasitology 38(3): 226-229.
Eyles, Don E. (1952) Incidence of Trypanosoma lewisi and Hepatozoon
muris in the Norway Rat. The Journal of
Parasitology 38(3): 222-225.
Eyles, Don E. (1950) A Stain for Malarial Oocysts in Temporary
Preparations. The Journal of Parasitology 36(5): 501.
Eyles, Don E. (1950) Quantitative studies on certain factors
influencing the development of Plasmodium gallinaceium
in the mosquito host. Thesis (Sc.D.) Johns Hopkins University, Baltimore,
Eyles, Don E. and J. Lynne Robertson, Jr. (1944) A guide and key
to the aquatic plants of the Southeastern United States. Washington, D. C.; United States Government
Goodwin, M. H., Jr.; Eyles,
Don E. (1942) Measurements of Larval Populations of Anopheles Quadrimaculatus, Say. Ecology 23(3): 376.
Eyles, Don E. (1941) A photosociological
study of the Castalia-Myriophyllum community of Georgia coastal
plain boggy Ponds. American
Midland Naturalist 26(2): 421-438.
1. Bruce-Chwatt, L. J. (1963) Dr. Don E. Eyles.
Nature 200 (4908): 733.
J. Faith and Cameron Binkley (ed.) 2003. Fort Pulaski National Monument
Administrative History. National Park
Service, Department of the Interior. Page
3. Barnes, Bart. October 10, 1963. “Dr. Don Eyles,
PHS Scientist” The
Washington Post, Times Herald, page C9.